Cancer Prone Disease Section
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چکیده
Note Ollier disease was first described by Louis Ollier, a French surgeon in early 1800s. The disorder is characterized by the presence of at least three enchondromas. Ollier disease manifests early in childhood and affects both sexes equally. Lesions are distributed unilaterally. In Ollier disease, enchondromas form in the medulla of mainly long bones and it is now clear that Ollier disease is a neoplastic disorder since genetic abnormalities were found in the enchondromas. As a result of the enchondromas the outer cortical layer of the bone becomes thin and more fragile. The disease has a unilateral predominance and may result in limb length discrepancy. The estimated prevalence of Ollier disease is 1/100,000.
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Cancer Prone Disease Section
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